ToxFAQs

Automotive Gasoline

CAS# 8006-61-9

September 1996


Automotive Gasoline
There is no molecular representation since this substance is a mixture of many compounds.
NFPA 130- Flammable
NFPA Label Key


Agency for Toxic Substances and Disease Registry


This fact sheet answers the most frequently asked health questions about automotive gasoline. For more information, you may call the ATSDR Information Center at 1-800-447-1544. This fact sheet is one in a series of summaries about hazardous substances and their health effects. This information is important because this substance may harm you. The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present.

SUMMARY: Exposure to automotive gasoline most likely occurs from breathing its vapor at a service station while filling a car's fuel tank. At high levels, automotive gasoline is irritating to the lungs when breathed in and irritating to the lining of the stomach when swallowed. Exposure to high levels may also cause harmful effects to the nervous system. Automotive gasoline has been found in at least 23 of the 1,430 National Priorities List sites identified by the Environmental Protection Agency (EPA).

What is automotive gasoline?
(Pronounced ah'to moe-tiv gas'uh-leen')

The gasoline discussed in this fact sheet is automotive used as a fuel for engines in cars. Gasoline is a manufactured mixture that does not exist naturally in the environment. Gasoline is produced from petroleum in the refining process. Gasoline is a colorless, pale brown, or pink liquid, and is very flammable.

Typically, gasoline contains more than 150 chemicals, including small amounts of benzene, toluene, xylene, and sometimes lead. How the gasoline is made determines which chemicals are present in the gasoline mixture and how much of each is present. The actual composition varies with the source of the crude petroleum, the manufacturer, and the time of year.

What happens to automotive gasoline when it enters the environment?

How might I be exposed to automotive gasoline?

How can automotive gasoline affect my health?

Animal testing is sometimes necessary to find out how toxic substances might harm people or to treat those who have been exposed. Laws today protect the welfare of research animals and scientists must follow strict guidelines.

Many of the harmful effects seen after exposure to gasoline are due to the individual chemicals in the gasoline mixture, such as benzene and lead. Inhaling or swallowing large amounts of gasoline can cause death.

Inhaling high concentrations of gasoline is irritating to the lungs when breathed in and irritating to the lining of the stomach when swallowed. Gasoline is also a skin irritant. Breathing in high levels of gasoline for short periods or swallowing large amounts of gasoline may also cause harmful effects on the nervous system.

Serious nervous system effects include coma and the inability to breathe, while less serious effects include dizziness and headaches.

There is not enough information available to determine if gasoline causes birth defects or affects reproduction.

How likely is automotive gasoline to cause cancer?

The Department of Health and Human Services (DHHS) and the International Agency for Research on Cancer (IARC) have not classified automotive gasoline for carcinogenicity. Automotive gasoline is currently undergoing review by the EPA for cancer classification.

Some laboratory animals that breathed high concentrations of unleaded gasoline vapors continuously for 2 years developed liver and kidney tumors. However, there is no evidence that exposure to gasoline causes cancer in humans.

Is there a medical test to show whether I've been exposed to automotive gasoline?

Laboratory tests are available that can measure elevated blood or urine levels of lead (as an indication of exposure to leaded gasoline only), benzene, or other substances that may result from exposure to gasoline or other sources. These methods are sensitive enough to measure background levels and levels where health effects may occur. These tests aren't available at most doctors' offices, but can be done at special laboratories that have the right equipment.

Has the federal government made recommendations to protect human health?

The EPA has established many regulations to control air pollution. These are designed to protect the public from the possible harmful health effects of gasoline.

The American Conference of Governmental Industrial Hygienists (ACGIH) set a maximum level of 890 milligrams of gasoline per cubic meter of air (890 mg/m3) for an 8-hour workday, 40-hour workweek.

Glossary

Carcinogenicity:
Ability to cause cancer
CAS:
Chemical Abstracts Service
Crude petroleum:
Petroleum that has not been processed
Dissolve:
To disappear gradually
Evaporate:
To change into a vapor or a gas
Irritant:
A substance that causes an abnormal reaction
Mixture:
A combination of two or more components
Refining process:
The process by which petroleum is purified to form gasoline
Tumor:
An abnormal mass of tissue

Reference

Agency for Toxic Substances and Disease Registry (ATSDR). 1995. Toxicological profile for automotive gasoline. Atlanta, GA.: U.S. Department of Health and Human Services, Public Health Service.

Where can I get more information?

ATSDR can tell you where to find occupational and environmental health clinics. Their specialists can recognize, evaluate, and treat illnesses resulting from exposure to hazardous substances. You can also contact your community or state health or environmental quality department if you have any more questions or concerns.

Agency for Toxic Substances and Disease Registry
Division of Toxicology
1600 Clifton Road NE, Mailstop E-29
Atlanta, GA 30333
Phone: 1-800-447-1544
Fax: 404-639-6359
U.S. Department of Health and Human Services
Public Health Service
Agency for Toxic Substances and Disease Registry


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